Genetic mutants of plasma apolipoprotein E - Apo E-5 and apo E-Suita.
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منابع مشابه
Apo A-i and Apo E Interaction: beyond Lipoproteins
Apolipoproteins (Apo) A-I, A-II, A-IV, and E possess repeated amphipathic helical regions with the same genomic structure and are members of a multigene family that probably evolved from a common ancestral gene [1]. These apolipoproteins play pivotal roles in lipid transport and lipoprotein metabolism, and their carboxyl-terminal domain is critical for lipid binding [2]. The purpose of this com...
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Apolipoprotein E (Apo E) is a basic component of very low-density lipoprotein (VLDL) and high-density lipoprotein (HDL). It plays an important role in the clearance of cholesterol from circulation, and thereby slows down the process of atherosclerosis. Its 3 isoforms, E2, E3 and E4 are encoded by 3 alleles, e2, e3 and e4, respectively. E3 is the most common isoform in most populations in the wo...
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Uremic dyslipidemia is an important risk factor for accelerated atherosclerosis, contributing to the many times higher cardiovascular mortality of hemodialysis (HD) patients (pts) in comparison to nonuremic population1. The influence of genetic determinants in this disorder has been widely studied, including apo E genetic variation and its relationship to cardiac and cerebrovascular disease. Ow...
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We have reported previously that canine livers possess two distinct lipoprotein receptors, an apoprotein (apo)-B,E receptor capable of binding the apo-B-containing low density lipoproteins (LDL) and the apo-E-containing cholesterol-induced high density lipoproteins (HDLc), and an apo-E receptor capable of binding apo-E HDLc but not LDL. Both the apo-B,E and apo-E receptors were found on the liv...
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The aim of the study was to investigate the association between methylenetetrahydrofolate (MTHFR) genotypes and levels of homocysteine (Hcy), folate, vitamin B12 and lipids as well as the association between apolipoprotein E (apo E) genotypes and levels of lipids in a Croatian healthy control group and a group of patients with > 70% carotid stenosis (CS). The study included 98 Croats, 38 patien...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 1985
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.74.62